ABSTRACT
Background: Pregnant women and fetuses are populations that are at high risk of being infected with the virus. COVID-19 in pregnant women is considered a risk factor for causing complications in pregnancy such as premature rupture of membranes. This study aims to analyze complications of premature rupture of membranes in mothers infected with COVID-19. Subjects and Method: This was a systematic review and meta-analysis. Article searches were conducted using electronic databases such as Google Scholar, PubMed and Science Direct. The articles used are articles published from 2020-2022. Keywords to search for articles were: "COVID-19" OR "2019-nCoV" OR "novel coronavirus" OR "SARS-CoV-2" OR "coronavirus 2" AND "premature rupture of membrane" OR "prelabour rupture of membrane" AND "pregnancy." The inclusion criteria used were full text articles in English with a cohort study design, multivariate analysis with Adjusted Odds Ratios (aOR), research subjects were pregnant women, intervention was COVID-19 infection, comparison was not infected with COVID-19, the outcome of the study was premature rupture of membranes. The results of the search for articles were included in the PRISMA diagram and analyzed using the Review Manager 5.3 application. Results: A total of 9 cohort study articles from the United States, Bangladesh, China, India, Mexico, Romania, and Spain were selected for systematic review and meta-analysis. The results showed that pregnant women infected with COVID-19 had a risk of complications of premature rupture of membranes as much as 2.26 times compared to pregnant women who were not infected with COVID-19 and the results were statistically significant (aOR = 2.26;95% CI = 1.33 to 3.82;p = 0.002). Conclusion: Pregnant women infected with COVID-19 increase the risk of premature rupture of membranes.
ABSTRACT
Background: On March 11, 2020, the World Health Organization (WHO) has declared an outbreak of a new coronavirus (COVID-19) as a global pandemic. In responding to the threat of the COVID-19 virus pandemic, policymakers have implemented a policy lockdown that can cause psychological distress, one of which is anxiety. This study aims to examine the effect of the policy lockdown on anxiety in adults using a meta-analysis. Subjects and Method: Meta-analysis was performed by searching for articles from the database, namely PubMed, Google Scholar, Science Direct, Scopus, and Crossref. The keywords used are "Anxiety" AND "Adult" AND "COVID-19" OR "SARS-CoV-2" AND "Lockdown" OR "Movement Restriction" OR "quarantine" OR "shutdown". The inclusion criteria in this study were full-text articles with a cross-sectional design, in English, published in the period 2019-2021. Analysis of the article using RevMan 5.3.